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Sunday, 23 November 2014 00:00

21. Highly Active Copper Catalysts for Azide-Alkyne Cycloaddition

Highly Active Copper Catalysts for Azide-Alkyne Cycloaddition, Zsombor Gonda, Zoltán Novák, Dalton Trans. 2010, 39, 726-729. DOI: 10.1039/b920790m | [Supp. Info Link]

Bis-triphenylphosphano complexes of copper(I)-carboxylates serve as efficient catalysts for azide-alkyne cycloaddition. The triazole formation takes place straightforwardly at ambient temperature providing a wide variety of products with good yields in the presence of 0.005–0.05% catalyst.

zng pub 21