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Sunday, 23 November 2014 00:00

25. Efficient Synthesis of Deuterated 1,2,3-Triazoles

Efficient Synthesis of Deuterated 1,2,3-Triazoles, Zsombor Gonda, Krisztán Lőrincz, Zoltán Novák, Tetrahedron Lett. 2010, 51, 6275-6277. DOI: 10.1016/j.tetlet.2010.09.097 | [Full Text Link]

A wide variety of 1-monosubstituted 1,2,3-triazoles were synthesized efficiently via a copper-catalyzed click-reaction between azides and acetylene gas, generated in situ from CaC2 with the addition of H2O or D2O.

zng pub 25