Login



Pull down to log in
×

Warning

JUser: :_load: Unable to load user with ID: 482
Sunday, 23 November 2014 00:00

33. Mild Palladium-Catalyzed Oxidative Direct ortho C-H aczlation of Anilides under Aqueous Conditions

Mild Palladium-Catalyzed Oxidative Direct ortho C-H aczlation of Anilides under Aqueous Conditions, Fruzsina Szabó, János Daru, Dániel Simkó, Tibor Zs. Nagy, András Stirling, Zoltán Novák, Adv. Synth. Catal. 2013, 355, 685-691. DOI: 10.1002/adsc.201200948 | [Full Text Link[Supp. Info Link]

Palladium-catalyzed cross-dehydrogenative coupling between anilides and aromatic aldehydes was achieved under aqueous conditions. A wide variety of the desired benzophenone derivatives was isolated in good to excellent yield. The reaction rate acceleration effect of acid and detergent has been demonstrated. Mechanistic insight has been obtained from quantum chemical calculations.

zng pub 33