Modular Copper-Catalyzed Synthesis of Chromeno[4,3-b]quinolines with the Utilization of Diaryliodonium Salts, Klára Aradi, Petra Bombicz, Zoltán Novák, J. Org. Chem. 2016, 81, 920-931. DOI: 10.1021/acs.joc.5b02490 | [Full Text Link] [Supp. Info. Link, CIF]
A novel, highly modular synthetic method with high functional group tolerance was developed for the construction of chromenoquinoline derivatives from arylpropynyloxy-benzonitriles and diaryliodonium triflates via an oxidative arylation–cyclization path. The copper(I) chloride catalyzed reaction is presumed to involve the formation of highly active arylcopper(III) species.