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ZNG Research

Our research group was formed in 2007 by Dr. Zoltán Novák associate professor at Eötvös Univeristy in Budapest, Hungary. In the beginning we focused on Palladium catalyzed cross-coupling reactions, however now the scope of our research covers the topic of C-H bond activation, Copper catalyzed reactions, Iron catalyzed reactions, Cross coupling via carbon-heteroatom bond cleavage, Solid supported catalysis, Photoredox catalysis, Domino reactions, Non-atmospherical pressure reactions and Total synthesis of small natural products.

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Eötvös Loránd University, Institute of Chemistry, Department of Organic Chemistry

kutatoegyetem(ELTE TTK) Eötvös Loránd Univeristy, Faculty of Science

News

  • First hit in 2018! Aromatic C-H Alkylation by Sulfonium Salts

    C−C bond-forming reactions via aromatic C−H bond activation processes have been studied in this paper. C−H activation based direct alkylations by alkyl group transfer are less explored in this field. However, the introduction of alkyl groups into aromatic systems, especially the ubiquitous methyl group in molecular scaffolds, could have beneficial effects on biological properties. This paper describes "Sulfonium Salts as Alkylating Agents for Palladium-Catalyzed Direct Ortho Alkylation of Anilides and Aromatic Ureas" presented by Dániel Simkó et. al. in Organic Letters (ACS). For further reading, please, Click here.

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    Written on Friday, 12 January 2018 15:07
  • OPR&D Highlights

    Our new publication entitled "Palladium Catalyzed 2,2,2-Trifluoroethoxylation of Aromatic and Heteroaromatic Chlorides Utilizing Borate Salt and the Synthesis of Trifluoro Analog of Sildenafil" had been picked up by the Highlights of OPR&D! The highlights are selected by a group of industrial chemists as a service to the readership who has a strong interest in practical chemistry that addresses and solves industrial questions.These trifluoroethoxylated compounds are both very useful and not always that easy to produce.

    Wenyi Zhao, Dongbo Zhao, Sylvain Guizzetti, James A. Schwindeman, David S. B. Daniels, Carlos A. Guerrero, Arjun Raghuraman, John Knight, Org. Process Res. Dev. ASAP, DOI: 10.1021/acs.oprd.7b00371 | [Full Text Link]

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    Written on Monday, 11 December 2017 12:38