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ZNG Research

Our research group was formed in 2007 by Dr. Zoltán Novák associate professor at Eötvös Univeristy in Budapest, Hungary. In the beginning we focused on Palladium catalyzed cross-coupling reactions, however now the scope of our research covers the topic of C-H bond activation, Copper catalyzed reactions, Iron catalyzed reactions, Cross coupling via carbon-heteroatom bond cleavage, Solid supported catalysis, Photoredox catalysis, Domino reactions, Non-atmospherical pressure reactions and Total synthesis of small natural products.

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Eötvös Loránd University, Institute of Chemistry, Department of Organic Chemistry

kutatoegyetem(ELTE TTK) Eötvös Loránd Univeristy, Faculty of Science

News

  • September starts with two new publications

    We are pleased to share our new papers.

    Aradi K. and her co-workers presented a mild N-arylation of nitroenamine derivatives utilizing diaryliodonium triflates and copper(I) chloride as a catalyst. For further reading, please, click here.

    zng pub 62

    Pethő B. and his co-workers developed a synthetic method for 2,2,2-trifluoroethoxylation of aromatic and heteroaromatic chlorides utilizing borate salt. Under palladium catalyzed reaction conditions an additional analog of Sildenafil was synthetized also. The paper was published in Chemistry - A European Journal (Wiley).For further reading, please, click here.

    zng pub 63

    Written on Sunday, 10 September 2017 14:57
  • New method for sequential coupling and deprotection of silyl alkynes

    Our group was presented a new syhtetic method for the desilylation of silylacetylenes via aquaous solution of hexafluorosilicic acid. The applicability of the novel, cheap and environmentally friendly reagent was demonstrated in the sequential coupling of aryl halides and ethynyltrimethylsilane to afford internal acetylenes, benzofurans, and triazoles in one-pot reactions. This paper has been published in Synthesis (Thieme) and entitled as "Hexafluorosilicic Acid as a Novel Reagent for the Desilylation of Silylacetylenes: Application in Sequential Sonogashira Coupling and Click Reaction". For further reading, please, click here.

    zng pub 60

     The applicability of the aqueous solution of the hexafluorosilicic acid was demonstrated in the sequential coupling of aryl halides and ethynyltrimethylsilane to afford internal acetylenes, benzofurans, and triazoles in one-pot
    Written on Thursday, 30 March 2017 14:00