Evaluation of bis-triphenylphosphano-copper(I)-butyrate (C3H7COOCu(PPh3)2) as catalyst for the synthesis of 1-(D-glycopyranosyl)-4-substituted-1,2,3-triazoles, Éva Bokor, Csenge Koppány, Zsombor Gonda, Zoltán Novák, László Somsák, Carbohydr. Res. 2012, 351, 42-48. DOI: 10.1016/j.carres.2012.01.004 | [Full Text Link]
Bis-triphenylphosphano-copper(I)-butyrate (C3H7COOCu(PPh3)2) was applied for the synthesis of O-peracylated 1-glycopyranosyl-4-substituted-1,2,3-triazoles from the corresponding glycosyl azides and alkynes. This catalyst proved superior to the CuSO4/l-ascorbic acid system even with sterically hindered and less reactive glycosyl azides.
