Synthesis, Structural Analysis and Application of Aryl‐Diadamantyl Phosphine ligands in Palladium Catalyzed Cross‐Coupling Reactions, Ádám Sinai, Dániel Csaba Simkó, Fruzsina Szabó, Attila Paczal, Tamás Gáti, Attila Bényei, Zoltán Novák, András Kotschy, Eur. J. Org. Chem. 2020, 9, 1122-1128. DOI: 10.1002/ejoc.201901834 | [Full Text Link] [Supp. Info. Link]

Synthesis, temperature dependent NMR structure investigation and utilization of a new, stable and easily accessible aryl‐diadamantylphosphine ligand family is reported. The bulky and electron rich phosphorous center of the ligand enhances the catalytic activity of palladium in cross‐coupling reactions of sterically demanded ortho substituted aryl halides. In our study we demonstrated the synthetic applicability of the new phosphine ligands in Buchwald‐Hartwig and tosyl hydrazone coupling reactions.