Efficient Copper-free Sonogashira Coupling of Aryl Chlorides with Palladium on Charcoal, Anna Komáromi, Zoltán Novák, Chem. Commun. 2008, 4968-4970. DOI: 10.1039/b810928a | [Supp. Info Link]

Palladium on charcoal serves as an efficient and reusable solid supported catalyst for the Sonogashira coupling of aryl chlorides with terminal acetylenes in the presence of a bulky, electron-rich biphenyl type ligand (XPhos), without copper co-catalyst.