Palladium-Catalyzed Methoxylation of Aromatic Chlorides with Borate Salts, Gergely L. Tolnai, Bálint Pethő, Péter Králl, Zoltán Novák, Adv. Synth. Catal. 2014, 356, 125-129. DOI: 10.1002/adsc.201300687 | [Full Text Link] [Supp. Info Link]

Herein we disclose a simple palladium-catalyzed transformation for the methoxylation of aromatic chlorides with tetramethoxyborate salts. The procedure provides a new and efficient synthetic tool for the introduction of a methoxy group into aromatic systems. In addition, the reaction can be achieved using a wide range of aromatic and heteroaromatic chlorides, the cheapest class of halides.