N-Halosuccinimide/SiCl4 as general, mild and efficient systems for the α-monohalogenation of carbonyl compounds and for benzylic halogenation, Tarek A. Salama, Zoltán Novák, Tetrahedron Lett. 2011, 52, 4026-4029. DOI: 10.1016/j.tetlet.2011.05.135 |
Combinations of N-halosuccinimide and tetrachlorosilane in acetonitrile were found to be efficient systems for the selective α-monohalogenation of carbonyl compounds as well as for benzylic halogenation under mild conditions.
